Chen Y-H, Tian W, Yasuda M, Ye Z, Song M, Mandel U, Kristensen C, Povolo L, Marques A R, Caval T, Heck A J R, Sampaio J L, Johannes L, Tsukimura T, Desnick R, Vakhrushev S Y, Yang Z, Clausen H (2023): A universal GlycoDesign for lysosomal replacement enzymes to improve circulation time and biodistribution. Front. Bioeng. Biotechnool, 11:1128371. DOi: 10.3389/fbioe.2023.1128371
Nason R, Bull C, Konstantinidi A, Sun L, Ye Z, Halim A, Du W, Sørensen DM, Durbesson F, Furukawa S, Mandel U, Joshi HJ, Dworkin LA, Hansen L, David L, Iverson TM, Bensing BA, Sullam PM, Varki A, Vries E, Haan C, Vincentelli R, Henrissat B, Vakhrushev S, Clausen H, Narimatsu Y (2021): Display of the human mucinome with defined O-glycans by gene engineered cells. Nat Commun 1;12(1):4070. DOI: 10.1038/s41467-021-24366-4.
Narimatsu Y, Bull C, Chen Y-H, Wandall HH, Yang Z, Clausen H (2021): Genetic glycoengineering in mammalian cells. J Biol Chem, 19;296:100448. DOI: 10.1016/j.jbc.2021.100448.
Schjoldager KT, Narimatsu Y, Joshi HJ, Clausen H (2020): Global view of human protein glycosylation pathways and functions. Nat Rev Mol Cell Biol, 21(12):729-749. DOI:10.1038/s41580-020-00294-x
Narimatsu Y, Joshi H, Nason R, Van Coillie J, Karlsson R, Sun L, Ye Z, Chen Y-H, Schjoldager KT, Steentoft C, Furukawa S, Bensing BA, Sullam PM, Thompson AJ, Paulson JC, Bull C, Adema GJ, Mandel U, Hansen L, Bennett EP, Varki A, Vakhrushev SY, Yang Z, Clausen H (2019): An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells. Mol Cell 75:1-14. DOI: 10.1016/j.molcel.2019.05.017
Tian W, Ye Z, Wang S, Schulz MA, Van Coillie J, Sun L, Chen Y-H, Narimatsu Y, Hansen L, Kristensen C, Mandel U, Bennett EP, Jabbarzadeh-Tabrizi S, Schiffmann R, Shen J-S, Vakhrushev SY, Clausen H, Yang Z. (2019): The Glycosylation Design Space for Recombinant Lysosomal Replacement Enzymes Produced in CHO Cells. Nat Commun. 10:1785. DOI: 10.1038/s41467-019-09809-3
Chen Y-H, Narimatsu Y, Clausen TM, Gomes C, Karlsson R, Steentoft C, Spliid CB, Gustavsson T, Salanti A, Persson A, Malmström A, Willén W, Ellervik U, Bennett EP, Mao Y, Clausen H & Yang Z (2018): The GAGOme: a cell-based library of displayed glycosaminoglycans. Nat Methods 15(11):881-888. DOI: 10.1038/s41592-018-0086-z
Schulz MA, Tian W, Mao Y, van Coillie J, Sun L, Larsen JS, Chen YH, Kristensen C, Vakhrushev SY, Clausen H, Yang Z. (2018): Glycoengineering design options for IgG1 in CHO cells using precise gene editing. Glycobiology 1;28(7):542-549. DOI: 10.1093/glycob/cwy022
Narimatsu Y, Joshi HJ, Zhang Y, Gomes C, Chen Y-H, Lorenzetti F, Furukawa S, Schjoldager K, Hansen L, Clausen H, Bennett EP, Wandall HH (2018): A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome. Glycobiology 1;28(5):295-305. DOI: 10.1093/glycob/cwx101
Lonowski LA, Narimatsu Y, Riaz A, Delay CE, Yang Z, Niola F, Duda K, Ober EA, Clausen H, Wandall HH, Hansen SH, Bennett EP, Frödin M (2017): Genome editing using FACS enrichment of nuclease-expressing cells and idel detection by amplicon analysis. Nat Protocols 12(3):581-603. DOI: 10.1038/nprot.2016.165
Yang Z, Wang S, Halim A, Schulz MA, Frodin M, Rahman SH, Vester-Christensen MB, Behrens C, Kristensen C, Vakhrushev SY, Bennett EP, Wandall HH, Clausen H. (2015): Engineered CHO cells for production of diverse, homogeneous glycoproteins. Nat Biotechnol 33:842-4. DOI: 10.1038/nbt.3280