The GlycoDisplay platform comprises panels of glycoengineered cell lines each producing different glycoforms, allowing display of the glycoforms on proteins. The patented solution applies targeted gene engineering in order to modify glycans. Unlike conventional glycan arrays, cell-based glycan array allows display of glycans in a natural context on the cell surface and is a sustainable resource to produce glycoproteins and to dissect biological functios of glycans. Using the GlycoDisplay technology we can engíneer any glycostructure on any protein, thus allowing pharmaceutical companies to effectively develop novel glyco-engineered biologics.
We have glycodisplay cell panels addressing:
-Different types of glycoconjugates, different branching and capping
-Drug formats like antibodies, cytokines, fusion proteins, lysosomal enzymes
-Simplified glycans for chemical coupling or more homogeneous product
Or we develop panels targeted to specific needs of partner.